J P N PHARMA PVT LTD Bangalore, Karnataka

A white to off white crystalline powder. Soluble in water and methanol, practically insoluble in acetone, chloroform, ethyl acetate. IR absorption spectrum of sample in KBR dispersion is concordant with that of reference standard of Tizanidine HCl. The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay.

A white or almost white crystalline powder. Freely soluble in water, slightly soluble in alcohol. The solution should clear and not more intensely colored than reference solution GY7. The solution is colourless. NMT 0.25 ml of 0.01 M NaOH is required to change the colour of the indicator of peak.

White or almost white crystalline powder. Soluble in water, practically insoluble in methylene chloride. It is sparingly soluble in dilute minerals acids and dissolves in dilute alkaline solutions. The solution is clear and not more intensely coloured than reference solution Y6.