Monitoring a Bin Blender by NIR - PAT
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The blending of pharmaceutical ingredients is one of the critical processes during the production of pharmaceuticals. Product homogeneity and further processing is dependant on the characteristics of the incoming material and process conditions. Sample taking and analysis at the end of the process is most commonly used for quality control, however this does not provide any information to enable optimisation of the process and doesn’t provide any process information. Applying online NIR to this process allows the determination of the blending end point by statistical methods. Beside this option the quantitative analysis of API or functional ingredients by applying a chemometric calibration is possible too. Based on the gained process data it is possible to optimize blending time, avoid faulty batches and prevent blend from being separated due to over-blending. There is no longer need for conventional thief sampling and laboratory analysis which retard manufacturing processes and therewith raise production costs. This makes a PAT solution to a very valueable tool in process and formulation development, up-scaling, and routine use. Fully implemented and applied the online monitoring of blend uniformity is a key element for real-time release.
Mixer Bin
75,000 - 168,000 Per Piece
1 Piece(s) (MOQ)
Produced out of premium grade supplies, our entire range is quality assured and conforms to global industry standards. We are acknowledged for providing only damage-free products to the clients. For this, we make use of quality and tamper-free packing materials along with sophisticated packing machines.
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