Pamidronate Disodium
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We are offering pamidronate disodium is the disodium salt of the synthetic bisphospho- nate pamidronate. Although it’s mechanism of action is not completely understood, pamidronate appears to adsorb to calcium phosphate crystals in bone, blocking their dissolution by inhibiting osteoclast-mediated bone resorption. This agent does not inhibit bone mineralization and formation. Pamidronate disodium salt is a bisphosphonate compound, which inhibits farnesyl diphosphate synthase & bone resorption. Studies suggest that pamidronate disodium salt stimulates polymorphonuclear leukocyte and platelet derived nitric oxide production. It is believed that this nitric oxide production can lead to a negative feedback mechanism, which could restrict the inflammatory process and reduce bone resorption. Furthermore, bisphosphonates induce endothelial cell death, cancer cell apoptosis, and nuclear factor-κb pathway activation, via the endothelial protein c receptor. synonyms: disodium; [3-amino-1-hydroxy-1-[hydroxy (oxido) phosphoryl] propyl] hydroxyphosphinate; pentahydrate cas number: 57248-88-1, mol. Formula: c3h9nna2o7p2.xh2o, mol.weight: 279.03 pamidronate disodium is white crystalline powder. It is soluble in water: 28 mgml with melting point of 300°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements
Idrona 30mg Injection
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Aredia 30mg Injection
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Pamidronate Disodium
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25 Kilogram (MOQ)
Pamidronate disodium is the disodium salt of the synthetic bisphospho- nate pamidronate. Although it’s mechanism of action is not completely understood, pamidronate appears to adsorb to calcium phosphate crystals in bone, blocking their dissolution by inhibiting osteoclast-mediated bone resorption. This agent does not inhibit bone mineralization and formation. Pamidronate disodium salt is a bisphosphonate compound, which inhibits farnesyl diphosphate synthase & bone resorption. Studies suggest that pamidronate disodium salt stimulates polymorphonuclear leukocyte and platelet derived nitric oxide production. It is believed that this nitric oxide production can lead to a negative feedback mechanism, which could restrict the inflammatory process and reduce bone resorption. Furthermore, bisphosphonates induce endothelial cell death, cancer cell apoptosis, and nuclear factor-κb pathway activation, via the endothelial protein c receptor.
Pamidronate Disodium
4,640 Per Vial
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Pamidronate Disodium / Acid
1 Per kg
1 Kilogram (MOQ)
Jigs chemical is global Manufacturer, supplier of Pamidronate disodium salt CAS no.57248-88-1, API, active pharmaceutical ingredients, intermediates, with documentation and certification, in India, China, UK, USA, Australia, Maxico, Canada, with DMF, CEP, COS, COPP. We offer as per requirements of RND/ Development quantities or commercials, Buy high quality source with supportive technical package. Pamidronate disodium salt CAS no.57248-88-1 API, active pharmaceutical ingredient to the pharmaceutical industry. Our Pamidronate disodium salt CAS no. 57248-88-1 is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product . We look forward to assisting you with your research and development projects. We offer from small R&D to commercial Quantity Pamidronate disodium salt CAS no.57248-88-1 with documentation like USDMF, EDMF, DMF (OPEN PART), DMF (CLOSED PART) CEP / COS, PMDA - JAPAN, DMF - CANADA, TGA - AUSTRALIA, , MHRA - UK, DMF - KOREA, AIFA - ITALY, TDP, HEALTH CANADA, MEDSAFE - NEW ZEALAND, , JDMF, JAPAN - AFM, DMF - CTD, DCGI, ICH, COPP, TDMF, Written Confirmation? Please contact us to send us sourcing request.
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White or almost white crystalline powder. Soluble in water, practically insoluble in methylene chloride. It is sparingly soluble in dilute minerals acids and dissolves in dilute alkaline solutions. The solution is clear and not more intensely coloured than reference solution Y6.
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