Pre-filled Syringe Filling and Rubber Stoppering Machine
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1 Unit (MOQ)
Pre-Filled Syringe Filling & Stoppering Machine Pre-Filled Syringe Filling Machine and Dental Cartridge Filling Machine, Pre Filled Syringe Stoppering Machine, Pre Filled Syringe Sealing Machine, Pre Filled Syringe Plunger Insertion Machine, and Pre Filled Syringe Labeling Machine consisting of the main structure covered polycarbonate cabinet and SS 304 pipe, laminar airflow, filling head with individual servo motor, out-feed collection tray, vacuum system, pneumatic components, and electrical panel, AC Drive, PLC & HMI. Syringe Filling Machine & Stoppering Machine loaded on Stainless Steel in-feed hopper. A prefilled syringe manufacturing process machine tray can directly be loaded onto the PFS machine. Duly filled & stoppered syringes delivered on outfeed collection tray without hand touch. Key Features The machine is manufactured or developed accordance with GMP standards. The structure is made of SS 304 or cladded with SS 304. Rigid vibration free construction for trouble free performance. Machine with out-feed trays for collection of syringe tub. All contact parts SS 316L and non-contact parts are SS 304. Machine suitable for different syringe size with help of change part and depends on characteristic of liquid. Servo with syringes synchronized system for filling Accuracy. Filling volume set with touch screen HMI. Pneumatically controlled Stoppering mechanism. Very easy & accurate electronic based volume setting of different pre-fill syringes. Zero Dripping filling stations. Diving system with the design of timer belt and Stepper Motor/pneumatic Control which has no Vibration and very smooth kind of filling, filling material must be Fill Centrally in the Syringe. Design of Nozzles and adjustment of flow rate is very useful for filling with minimum Air Bubble / foaming in the Syringes. Low air machine stop sensor. LAF stop machine stop sensor. Door interlocking system. A suitable expandable PLC with programming & 7” colour touch screen HMI. The Pharma grade silicon tubes are used for filling & CIP/SIP. There is a very less product change over time due to very less usage of mechanical parts. All liquid contact parts easily removable for cleaning and sterilization purpose. Machine with LAF which can maintain class 100 condition (OPTIONAL). Co eccentric nozzles for quick filling of liquids. For different heights of syringes, the whole assembly can be moved upwards & downwards. Production counter is given with password protection for daily track report. The faults can be detected on the PLC touch screen HMI and can be attended easily. The output speed can be appeared on HMI screen. Very less mechanical adjustment required due to the special design. User friendly and very less maintenance required. NITROGEN FLUSHING SYSTEM [OPTIONAL]: The filling unit has an inbuilt system for nitrogen flush. The unique dual filling nozzle flushes nitrogen before filling followed by filling operation. Most reliable & proven mechanical components such as pneumatics & CE certified electrical/electronic such as AC motor, AC Drives, PLC & HMI Touch screen, safety interlock & Sensors, MCB’s, relay etc.
Automatic Injectable Powder Filling with Rubber Stoppering Machine
800,000 Per Piece
1 Piece (MOQ)
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Six Head Vial Filling With Rubber Stoppering Machine
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Automatic Injectable Liquid Filling Machine with Rubber Stoppering Unit
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Glass Vial Liquid Filling Rubber Stoppering Machine
215,000 - 2,850,000 Per Piece
1 Piece (MOQ)
Glass Vial Liquid Filling & Rubber Stoppering Machine is suitable for Round Vials with maximum speed of 240 Vials per minutedepending on nature of Liquids, Vial Neck Size, Fill Volume and Rubber Stopper size. Machine construction in fully Stainless-Steel finish including machine frame structure. Machine with built-in Turn Tables at In-feed and Out-feed with individual drives to match the speed of incoming and outgoing vials for smoother operation. All parts coming in contact with Liquids and Rubber Stoppers are made from SS 316 Materials. Machine also available with vaccumetric type Rubber Stoppering System. Special Features: Total Controls on your figure tips. Servo based filling volume adjustment. Easy to adjust filling volume from PLC screen. Easy to maintain and changing spare part, changing format form for different vial sizes. Suitable for the filling Volume of 2ml to 100ml. Volume adjustment by pic controls. Provision of Manually fine volume adjustment Higher accuracy with higher speed due to servo control continuous motion. Provision of half and full stoppering. Inbuilt Scrambler &Unscr ally or fully stopper filled vials. Vial filling machine shall be equipped with eject collect tray for un stopper Vials. Provision for inert gas purging – pre and post the filling. Rejected without stopper vial shall be store in a safe condition, Vial filling machine shall perform the following functions. Vial half stoppering. Nitrogen purging (pre and post fill). Fallen vial eject, no stopper ejects. Ambler with rejected vial collect facility. Rigid vibration free construction for trouble free performance Pick and place type stoppering machine Vial filling machine shall be equipped with pumps with an accuracy of 0.5 on the fill volume. Suitable for Plain as well as Slotted Stoppers, with the help of change parts High Precision manufactured Syringes (2 Nos.) Servo Motor driven Syringes
Vial Filling machine,Vial stoppering Machine
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The Vial Filling and Stoppering Machine has been manufactured specifically to be used for filling injectable glass vials. The basic components of the vials liquid filling machine includes a turntable, conveyor belts made of stainless steel, unique eccentric pre-gassing, filling and other post-gassing aspects. The syringes are made of excellent quality 316L stainless steel. Apart from this, it consists of non-toxic tubing made of synthetic rubber of reliable and durable quality. Furthermore, the compact panel is easy to access, reach and use. Since the area between the machine that is responsible for filling the vials and the one responsible for stoppering the vials is less, hence, the risk of the contamination reduces considerably. It is very important to understand that the machine has been made to work specifically in a sterile environment to ensure that there is no contamination. These are designed for use under the laminar flow protection itself. The redesigning of the un-scrambler has been done to reduce the dead ends and increase efficiency of the spots that are difficult to clean. This is of compact cGMP model This is ideal for filling vials of 2ml to 250ml These are for piston pump/peristaltic pumps filling It provide high accuracy rate There is a system of No Vial-No filling and No Vial-Machine Stop to reduce wastage Systematic auto filling of the objects is designed through in-feed turn tables Reduction in any sort of cross contamination Easy validation processes A/C frequency setup to easily adjust the velocity Validation systems for cross check of bulk production Online mechanism Documentation through IQ/OQ Optional system of PLC with Graphical user interface
Stoppering Machine
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AUTOMATIC HIGH SPEED POWDER FILLING FOR INJECTABLE WITH RUBBER STOPPERING MACHINE. Legend Automatic Injectable Powder Filling with Rubber Stoppering Machine is a versatile machine suitable for Round Vials with an optimum Production Rate of various fill rates.Machine is provided with in-built Turn Tables at In-feed and Out-feed with individual drives to match the speed of incoming and outgoing vials for smoother operation. The Machine is equipped with Single Head Single Track Eight Port Powder wheel, which works on Vacuum and Air Systems to fill powder in Vials.
High Speed Automatic Sterile Injectable Powder Filling cum Rubber Stoppering Machine
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The machine will have single hopper & single wheel each the track. Negligible powder spillage will be there between hopper & wheel. Parts / Assemblies required to be autoclaved will be easily removable and reset with user friendly assemblies.
PRE-FILL SYRINGE FILLING AND STOPPERING SYSTEM
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System With Unique De-Nester System Individual PFS Filling & Stoppering For Validation Of Individual Syringe Compact Footprint 21CFR Part 11 Compliance Suitable for Aqueous & Viscous Drugs Filling Accuracy @ (+/-) 0.02ml In 0.2ml Fill Fill Volume Spectrum : 0.2 Ml To 10 Ml (Change Part Supported) Servo Driven System
Automatic Vial Filling and Rubber Stoppering Machine
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Automatic Vial Filling & Rubber Stoppering Machine is compact model uses for the filling & rubber stoppering of injectable liquid vials. Adinath offers different models of Vial Filling & Rubber Stoppering Machine suitable for pharmaceutical industry. Our Automatic Six Head Vial Filling & Rubber Stoppering Machine provides output up to 9000 vials/hour suitable for large batch production, Our Automatic Four Head Vial Filling & Rubber Stoppering Machine provides output up to 7200 vials/hour suitable for medium batch production and Our Automatic Two Head Vial Filling & Rubber Stoppering Machine which provides output up to 3600 vials/hour suitable for medium & small batch productions. Our Vial Filling Machines are easy to operate & complies as per cGMP standards. Our standard machine equipped with stainless steel piston pump for the liquid filing, further we can also provide peristaltic pump for higher filling accuracy upon specific customer request. Salient Features No cross contamination. Suitable for the filling Volume of 2ml to 250ml. Piston pump/Peristaltic pump aseptic filling. Filling with accuracy of ±0.5-1%. Easy to validate filling system for small/large batch production. All Contact Parts Made from S.S 316L & framework by S.S. 304. Variable A.C. frequency drive for speed adjustmentDigital Vial Counter for counting production output. In-feed Turn Table/ Unscrambler for automatic feeding of objects. On-line Mechanism. “No Vial - No Filling" system. “No Vial - Machine Stop" system. IQ/OQ documentation can be provided. PLC with Graphical User Interface. (Optional) Process Operation The incoming dry vial (sterilized and siliconised) are fed through the unscrambler and suitably guided on the moving delrin slat conveyor belt at the required speed of the correct placement below filling unit. The filling unit consists of Filling Head, Syringes & Nozzles which are used for liquid filling. The syringes are made of S.S. 316 construction and both, glass as well as S.S. syringes can be used. A Star Wheel is provided which holds the vial during filling operation. A sensor is provided
Sterile Vial Powder Filling Stoppering Machine
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Rubber Stoppering Machine
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Vial Filling With Rubber Stoppering Machine With Diving Nozzles. The Unit Is Made Compact, Versatile And Enclosed In Stainless Steel Elegantly Matt Finish Body, Consists Of Delrin Conveyor, Reciprocating Nozzle With Self-centering Devices & SS Syringe.
Pre Filled Syringe Filling And Stoppering Machine
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Monoblock pre Filled Syringe filling and Stoppering machine Model - CPPFS is very compact and elegant PLC based GMP model for automatic filling and Stoppering operation of pre filled syringe. Operator has to keep a nest (tray) of 100 pre filled syringes over the SS jig. Then he has to put a jig to filling magazine and start the machine to filled syringes. Operator has to keep a nest (tray) of 100 pre-filled syringes over the SS jig. Then he has to put a plugs tray with suitable stoppers over the SS-316 plug tray. Then after he has to close the evacuation and Stoppering chamber. Now he can start the machine. Automatic Filling cycle start one by one as per the programmed Stoppering cycle mentioned as under. 100 stoppers are plugged into the pre-filled syringes precisely after vacuum hold cycle. Now last cycle of nitrogen flushing with vacuum break completes the Stoppering operation. PROGRAM CYCLE FOR EVACUATION AND STOPPERING Cycle Operation 1 Vacuum evacuation in the chamber 2 Nitrogen Flushing. 3 Vacuum Evacuation repeats. 4 Nitrogen flushing repeats. 5 Vacuum creation with hold. 6 Plunging of stopper inside the pre-filled syringes 7 Nitrogen purging cycle with Vacuum break. SALIENT FEATURES: Model : PFS - 05 is a compact, elegant and matt - finished encompassed with stainless steel (SS-304) Perfect synchronization of PLC based cycle, filling stroke and Syringes to fill volume for 1ml to 5ml Compact and feather-touch MMI control panel for easy control of the machine operation The machine is equipped with easily adjustable leveling legs so foundation is not required. Nitrogen filter is provided pre-filter 0.5u. and final filter is 0.2u. air ex. Is 0.2u. UTILITIES Sterile air and nitrogen Important Requirements 1 Vacuum pump is to be installed outside the sterile area. 2 Silicon tubes are under the scope of customer 3 Water line is required for cooling of vacuum pump chambers PERFECT SYNCHRONIZATION OF PLC
Vial Filling Stoppering Machine
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Salient Features Inbuilt Scrambler & Unscramble. 24". Suitable For 2 ml to 100ml vial. No vial no filling. No stopper machine stop. Rigid vibration free construction for trouble free performance. S.S. Elegantly matt-finished body. Elegant and easy control panel for total control on operation. Minimum change over time from one size to another container or fill size. Drip Trey provided.
Stoppering Machine
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Direction;Left to Right,Production Rate ;Up to 100 to 120 VialsMin. (For 5ml. fill size),Fill Capacity ;0.5 ML to 100 ML ( Up to 50 ML single dose & for 100 ML double dose),Power Requirement;415 Volts, 3 Phase (4 Wire System), 50 Hz.
Rubber Stoppering Machine
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Automatic Four Head Volumetric Motion type Liquid Vial Filling with Vacuumetric Rubber Stoppering Machine Model LF-120 is suitable for Round Vials with maximum speed of 120 Vials per minute depending on nature of Liquids, Vial Neck Size and Fill Volume. Machine construction in fully Stainless Steel finish including machine frame structure. Machine with unique motion filling system, Filling Nozzle moves alongwith Vials during the Liquid Filling Process without stoppage of Vials and also with time tested Vaccumetric Rubber Stoppering System for positive placement of Rubber Stopper on Vials at higher speed. All parts coming in contact with Liquids and Rubber Stoppers are made from SS 316L Materials. TECHNICAL SPECIFICATIONS Vial Diameter : 15mm to 50mm* Vial Height : 75mm Maximum* Rubber Stopper Diameter : 13mm and 20mm Dry or Wet Grey Butyl Fill Range : 1ml to 50ml with help of Change Parts / Syringes Accuracy : +/- 1% Depending on Liquid with Single Dose Electrical : 220 VAC Single Phase Power Supply Power : 3.0 H.P. Speed : upto120 per minuite, Syringe Fill Range: 0.1ml to 1ml, 1ml to 5ml, 2ml to 10ml and 10ml to 50ml Conveyor Height : 800-850 mm Overall Dimensions : 1200 mm (L) x 1100 mm (W) x 1400 mm (H)
Stoppering Machine
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Machine is a compact, elegant and matt (Dull) finished encompassed with stainless steel (SS 304) Viscous substance (1 ml to 3 ml).Accurately with the help of change parts Perfect synchronization of filling and stoppering cycles through pneumatically controlled stoppering mechanism.Very easy & accurate electronic based Volume setting of different prefill syringes.Diving system with the design of Germany make ball screw and stepper motor control which has no vibration and very smooth kind of filling and system itself take care that, filling material must be fill centrally in the syringe
Stoppering Machine
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Pre Filled Syringe Filling & Stoppering Machine Model PFS-SA-10 is very compact and elegant PLC. Based cGMP model for automatic filling and Stoppering operation of pre filled syringe.
Stoppering Machine
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The incoming dry Vial (sterilized and siliconised) are fed through the unscrambler and suitably guided on the moving delrin slat conveyor belt at the required speed of the correct placement below filling unit. The filling unit consists of Filling Head, Syringes & Nozzles which are used for liquid filling. The syringes are made of SS 316 construction and both, glass as well as SS syringes can be used. A Star Wheel is provided which holds the vial during filling operation. A sensor is provided. On same station the Filled Vial pick the Rubber Stopper from Vibratory Bowl to the help of Delivery Suite and place the Stopper on Vial using the Roller pressure. The Vial is move for the Next Operation.
Automatic Four Head Vial Filling and Rubber Stoppering Machine
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AUTOMATIC High Speed LIQUID Vial Filling & VACUUM Rubber Stoppering Machine MODEL: AHVF 4, 6 & 8 Description: High Speed Automatic Vial Filling & Rubber Stoppering Machine suitable for the filling & rubber stoppering of glass vials. Our Automatic Vial Filling & Rubber Stoppering Machine is widely uses in SMALL & large volume injectable preparations. Machine consist automatic feeding, filling, bunging & ejection system all complies as per cGMP requirements. Automatic Vial Filling & Rubber Stoppering Machine can be attached to Vial Washing Machine and Vial Cap Sealing Machine in order to complete online Sterile Vial Filling Line. Machine complies as per GMP requirements. Our standard machine equipped with stainless steel piston pump for the liquid filing, further we can also provide peristaltic pump for higher filling accuracy upon specific customer request. Salient Features: • Suitable for the filling Volume of 2ml to 250ml. • Piston pump/Peristaltic pump aseptic filling. • Filling with accuracy of ±0.5-1% • Filling with accuracy of ±0.5-1%. • All Contact Parts Made from S.S 316L & framework by S.S. 304. • ariable A.C. frequency drive for speed adjustment. • Digital Vial Counter for counting production output. • In-feed Turn Table/ Unscrambler for automatic feeding of objects. • On-line Mechanism. • “No Vial - No Filling” system. • “No Vial - Machine Stop” system. • IQ/OQ documentation can be provided Process Operation: The incoming dry vial (sterilized and siliconised) are fed through the unscrambler and suitably guided on the moving delrin slat conveyor belt at the required speed of the correct placement below filling unit. The filling unit consists of Filling Head, Syringes & Nozzles which are used for liquid filling. The syringes are made of S.S. 316 construction and both, glass as well as S.S. syringes can be used. A Star Wheel is provided which holds the vial during filling operation. A sensor is provided for 'No Vial-No Filling' operation. Syringes are mounted on eccentric block and driving through bottom main gear box. Volume can be either increased or decreased by increasing or decreasing stroke length of piston as per filling size. Syringes is having non return valve for sucking and delivering situation to avoid volume variation. Liquid will reach to filling nozzles through silicon transparent pipe. Nozzle will be having Up and Down movement with help of cam mechanism and it will come down when vial will be hold by starwheel for filling operation and starts filling when it starts to move up and after completion of filling operation, starwheel delivers six vials together on conveyor for rubber stoppering operation.