high pressure reactor
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A pressure reactor can offer several advantages over the conventional round-bottom flask. Firstly, it can conduct a reaction above the boiling point of a solvent. Secondly, the pressure can reduce the reaction volume, including the liquid phase, and in turn increase concentration and collision frequency, and accelerate a reaction. Increase in temperature can speed up the desired reaction, but also speed up the decomposition of reagents and starting materials. However, pressure can speed up the desired reaction and only impacts decomposition when it involves the release of a gas or a reaction with a gas in the vessel. When the desired reaction is accelerated, competing reactions are minimized. Pressure generally enables faster reactions with cleaner reaction profiles. The above benefits from a pressure reactor has been shown in microwave chemistry. E.g., if a Suzuki Coupling takes 8 hours at 80°C, it only takes 8 minutes at 140°C in a microwave synthesizer. The microwave effect is a controversial topic. Later experiments show some of these early reports to be artifacts and rate enhancement is strictly due to thermal effects. If a pressure reactor is engineered properly, it can meet 4 out of 12 green chemistry principles 1, less solvent and cleaner reaction profile result in less waste 5, less solvent is needed 6, short reaction time can save up to 92 percent electricity and 200 gallons of cooling water per refluxed reaction. 12, closed vessel can prevent releasing toxic gas and explosions.
Series 5500 High Pressure Compact Laboratory Reactors
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Series 5500 High Pressure Compact Laboratory Reactors
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high pressure reactor
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