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Osicent 80mg (Osimertinib) Azd9291 generic Tagrisso for Lung cancer treatment Osicent 80mg (Osimertinib) AZD9291 Generic Tagrisso short description: Osicent (Osimertinib) Azd9291 is kinase inhibitor of the epidermal growth factor receptor (EGFR). Which binds irreversibly to certain mutant forms of EGFR (T790M, L858R, and exon 19 deletion) at approximately 9-fold lower concentrations than wild-type. In cultured cells and animal tumor implantation models, Osimertinib exhibited anti-tumor activity against Non- Small Cell Lung Cancer (NSCLC) lines harboring EGFR-mutations (T790M L858R, L858R, T790M exon 19 deletion, and exon 19 deletion). Also to a lesser extent, wild-type EGFR amplifications.

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