Busulfan Tablet Dealers in Mumbai

• Supplied By: UMA Brothers, India

We are offering busulfan. An alkylating agent having a selective immunosuppressive effect on bone marrow it has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. According to the fourth annual report on carcinogens (ntp 85-002, 1985), busulfan is listed as a known carcinogen. Busulfan is an alkylating drug. The mechanism of action of busulfan is as an alkylating activity. Busulfan is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of dna. Following systemic absorption of busulfan, carbonium ions are formed, resulting in dna alkylation and dna breaks and inhibition of dna replication and rna transcription. synonyms: 4-methylsulfonyloxybutyl methanesulfonate cas number: 55-98-1, mol. Formula: c6h14o6s2, mol.weight: 246.3 busulfan is a white needles powder. It is soluble in acetone, 100% ethanol or dmso; insoluble in water with melting range of 114°c to 117°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

• Category: Anti Cancer Tablets
• Dosage: 5mg
• Grade Standard: Medicine Grade
• Storage: Cool and Dry Place
• Form: Tablets / Liquid / Capsules / Powder
• Packaging Type: Plastic Bottle
• Storage: Cool and Dry Place
• Usage: Clinical, hospital etc.

Busulfan tablets contain a medicine called busulfan. This belongs to a group of medicines called cytotoxics (also called chemotherapy). Busulfan is used for certain blood problems and cancers of the blood. It works by reducing the number of new blood cells your body makes. Busulfan is used for Chronic granulocytic leukaemia (also called chronic myeloid leukaemia) – a disease that increases the number of white blood cells. 3s corporation is supplier, Exporter  for Busulfan 2 mg tablets in India.   ADDITIONAL INFORMATION The recommended dose of busulfan in adult patients is 1 mg/kg every 6 hours for four days, starting seven days prior to transplantation. 60 mg/kg per day of cyclophosphamide is usually given for two days commencing 24 h after the final dose of Busulfan.     SIDE EFFECTS Toxicity may include interstitial pulmonary fibrosis (“Busulfan Lung”), hyperpigmentation, seizures, hepatic (veno-occlusive disease) (VOD), emesis, and wasting syndrome. Busulfan also induces thrombocytopenia, a condition of lowered blood platelet count and activity. Seizures and VOD are serious concerns with busulfan therapy and prophylaxis is often utilized to avoid these effects. Hepatic VOD is a dose-limiting toxicity. Antiemetics are often administered prior to busulfan to prevent emesis.