8 hydroxy quinoline
8-Hydroxyquinoline has a wide variety of uses, primarily due to its metal chelating properties. 8-Hydroxyquinoline and its salts, halogenated derivatives, and metal complexes have been utilized as analytical reagents (Hollingshead, 1954) and as antimicrobial agents in medicine, fungicides, and insecticides (Harvey, 1975). Additionally, it serves as a preservative in cosmetics and tobacco, a chemical intermediate in dye synthesis (IARC, 1977), and a precipitating reagent for uranium and other radioactive metals in nuclear power plant liquid waste effluent. It is also employed in nuclear medicine with indium-111 (Davis et al., 1978).
...more8 hydroxy quinoline
8-Hydroxyquinoline has a wide variety of uses, primarily due to its metal chelating properties. 8-Hydroxyquinoline and its salts, halogenated derivatives, and metal complexes have been utilized as analytical reagents (Hollingshead, 1954) and as antimicrobial agents in medicine, fungicides, and insecticides (Harvey, 1975). Additionally, it serves as a preservative in cosmetics and tobacco, a chemical intermediate in dye synthesis (IARC, 1977), and a precipitating reagent for uranium and other radioactive metals in nuclear power plant liquid waste effluent. It is also employed in nuclear medicine with indium-111 (Davis et al., 1978).
Brand Name : DOPRAN PHARMA
EINECS No. : 205-711-1
Purity : 99 %
Type : NA
MF : CD00006807
Country of Origin : India
...moreDoxycycline Hydrochloride
Doxycycline hydrochloride is a salt prepared from doxycycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, doxycycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis.Doxycycline hydrochloride, is used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks. It is a broad spectrum inhibitor used to inhibit matrix metalloproteinases (MMP), such as type 1 collagenase in studies on wound healing and tissue remodeling.
Brand Name : DOPRAN PHARMA
Color : Yellow
Form : Powder
Chemical Formula : C22H25ClN2O8
Application : NA
Grade : 99%
Packaging Type : 25 KG
Packaging Size : 25
Purity (%) : 99%
Molecular Weight : 480.9
Cas Number : 10592-13-9
...moreDoxycycline Hydrochloride
Doxycycline hydrochloride is a salt prepared from doxycycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, doxycycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis.Doxycycline hydrochloride, is used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks.
Brand Name : DOPRAN PHARMA
Color : Yellow
Form : Powder
Chemical Formula : C22H25ClN2O8
Application : NA
Certification : NA
Grade : 99%
Packaging Type : 25 KG
Packaging Size : 1kg,5 Kg,10 Kg,25kg
Purity (%) : 99%
Country of Origin : India
Molecular Weight : 480.9
Speaciality : Highly Effective, No Side Effect
Storage Conditions : Inert atmosphere,2-8°C
Protein (%) : 90%
Calories (%) : 90%
Prescription : Prescription
Cas Number : 10592-13-9
...moreDoxycycline Hydrochloride
Brand Name : DOPRAN PHARMA
Color : yellow
Type : NA
Application : NA
Weight : 480.9
MF : CD03427564
EINECS No. : 234-198-7
Purity : 99 %
Appearance : NA
Form : powder
Melting Point : 195-201℃
Packaging Size : 1kg,5 kg, 10 kg,25kg
...moreAlbendazole Powder
400 - 600 Per Kilogram
Albendazole is a derivative of benzimidazole, is a drug with a broad antihelmintic spectrum. It exhibits an antihelmintic effect against sensitive cestodes and nematodes by blocking the process of glucose uptake by the parasites, which is expressed in the depletion of glycogen reserves and subsequent reduction in the level of adenosintriphophate. As a result, the parasite stops moving and dies. It is used upon infection of Acaris lumbricoides, Ancylostoma duodenale, Necator americanus, Enterobius vermicularis, and Trichuris trichiura. Synonyms of this drug are SKF 62979 and others.
Application : NA
Brand Name : DOPRAN PHARMA
Color : White To Off-White
Form : Neat
CAS No. : 54965-21-8
EINECS No. : 259-414-7
Packaging Size : 1kg,5 Kg, 10 Kg,25kg
Type : NA
Country of Origin : India
...moreAlbendazole Powder
400 - 600 Per Kilogram
25 Kilogram (MOQ)
Poorly absorbed from the gastrointestinal tract due to its low aqueous solubility. Oral bioavailability appears to be enhanced when coadministered with a fatty meal (estimated fat content 40 g)Symptoms of overdose include elevated liver enzymes, headaches, hair loss, low levels of white blood cells (neutropenia), fever, and itchingAlbendazole occurs as a white to faintly yellowish powder. It is practically insoluble in water and alcohol, very slightly soluble in ether and dichloromethane, but freely soluble in anhydrous formic acid.Albendazole is a derivative of benzimidazole, is a drug with a broad antihelmintic spectrum. It exhibits an antihelmintic effect against sensitive cestodes and nematodes by blocking the process of glucose uptake by the parasites, which is expressed in the depletion of glycogen reserves and subsequent reduction in the level of adenosintriphophate. As a result, the parasite stops moving and dies. It is used upon infection of Acaris lumbricoides, Ancylostoma duodenale, Necator americanus, Enterobius vermicularis, and Trichuris trichiura. Synonyms of this drug are SKF 62979 and others.For the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.ChEBI: Albendazole is a carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a propylsulfanyl group at position 5. It is commonly used in the treatment of parasitic worm infestations. It has a role as a tubulin modulator, a microtubule-destabilising agent and an anthelminthic drug. It is a carbamate ester, a benzimidazolylcarbamate fungicide, an aryl sulfide and a member of benzimidazoles.A mixture of 6.65 g of 3-chloro-6-nitroacetanilide, 3.2 ml of propylmercaptan, 5.6 g of 50% sodium hydroxide and 100 ml of water is heated at reflux overnight. The cooled mixture is filtered to give the desired 2-nitro-5- propylthioaniline, MP 69.5-71.5°C after recrystallization from ethanol then hexane-ether. NMR (CDCl3) 40%.The aniline (2.5 g) is hydrogenated with 1.9 ml of concentrated hydrochloric acid, 100 ml ethanol and 5% palladium-on-charcoal to give 4-propylthio-ophenylene- diamine hydrochloride.
Application : Pharma Industries
Brand Name : DOPRAN PHARMA,dopran pharma
Material : Albendazole
Color : White to Off-White
Form : Solid
Dosage Form : 99%
CAS No. : 54965-21-8
EINECS No. : 259-414-7
Packaging Type : 25 KG
Packaging Size : 1 kg,5 kg, 10 kg,25kg
Type : NA
Function : Practically insoluble in water, freely soluble in anhydrous formic acid, very slightly soluble in me
Animal Type : neat
Warranty : 98%
Country of Origin : India
Prescription/Non Prescription : Prescription
...moreFenbendazole
400 - 600 Per Kilogram
25 Kilogram (MOQ)
Fenbendazole is a benzimidazole anthelmintic. It is active against Giardia in vitro (IC50 = 0.3 μM). Fenbendazole (20 mg/kg) prevents infiltration of parasites into the brain in a rabbit model of E. cuniculi infection. Fenbendazole also activates HIF-1α and prevents oxidative stress-induced death in primary neurons in vitro.Fenbendazole is a benzimidazole anthelmintic that is metabolised in mammals to a series of other benzimidazoles including oxfendazole. It is used for the control of gastrointestinal roundworms, lung worms, Nematodes and tape worms. It is the only benzimidazole approved for use in organic livestock production.Fenbendazole is a medication used to treat parasites, mainly in dogs. However, studies have found that in a group of mice treated with a combination of fenbendazole and vitamins, tumor growth inhibition was unexpected It may be because it interferes with the uptake of glucose by cancer cells, which is essential for tumor growth and proliferation. It prevents cancer cells from obtaining the glucose needed to grow and divide to inhibit the growth of cancer cells. Studies have found that fenbendazole can kill cancer cells and promote tumor regression in patients with metastatic large B-cell lymphoma, and also plays a role in other metastatic malignant tumors such as bladder cancer and renal cell carcinoma. It is currently being treated in combination with other anti-cancer drugs to study its anti-cancer potential[1-3].20.9 g of S-methyl-thiourea were dissolved in 27 ml of water with 13.5 ml of chloroformic acid methyl ester. Then, 45.7 ml of 25% sodium hydroxide solution were added dropwise, while stirring, at a temperature of 5°C to 10°C. After having stirred for 20 minutes, the reaction mixture was combined with 27 ml of glacial acetic acid, 100 ml of water and 29 g of 3,4-diaminodiphenyl- thioether. Stirring was continued for 90 minutes at a temperature of 85°C, during which time methyl-mercaptan was separated. After having allowed the whole to cool and stand overnight, the 5-phenylmercaptobenzimidazole- 2-methyl-carbamate that had formed was filtered off with suction. After recrystallization from a mixture of glacial acetic acid and methanol, 14 g of 4-phenylmercapto-benzimidazole-2-methyl-carbamate melting at 233°C were obtained.Fenbendazole is indicated (labeled) for the removal of the following parasites in dogs: ascarids (Toxocara canis, T. leonina), Hookworms (Ancylostoma caninum, Uncinaria stenocephala), whipworms (Trichuris vulpis), and tapeworms (Taenia pisiformis). It is not effective against Dipylidium caninum. Fenbendazole has also been used clinically to treat Capillaria aerophilia, Filaroides hirthi, and Paragonimus kellicotti infections in dogs.Fenbendazole is indicated (labeled) for the removal of the following parasites in cattle: Adult forms of: Haemonchus contortus, Ostertagia ostertagi, Trichostrongylus axei, Bunostomum phlebotomum, Nematodirus helvetianus, Cooperia spp., Trichostrongylus colubriformis, Oesophagostomum radiatum, and Dictyocaulus vivaparus. It is also effective against most immature stages of the above listed parasites. Although not approved, it has good activity against Moniezia spp., and arrested 4th stage forms of Ostertagia ostertagi. Fenbendazole is indicated (labeled) for the removal of the following parasites in horses: large strongyles (S. edentatus, S. equinus, S. vulgaris), small strongyles (Cyathostomum spp., Cylicocylus spp., Cylicostephanus spp., Triodontophorus spp.), and pinworms (Oxyuris equi).Fenbendazole is a benzimidazole antiparasitic drug that works at the sub-cellular level preventing cell division. Benzimidazoles bind to the β-tubulin, inhibiting the cell’s microtubule assembly responsible for intracellular transport and required for mitotic cellular division. In effect, it starves the parasite by causing intestinal cell disruption.[1] Gao P, et al. Unexpected antitumorigenic effect of fenbendazole when combined with supplementary vitamins. Jour
Brand Name : DOPRAN PHARMA
Molecular Formula : C15H13N3O2S
Grade : 99%
Packaging Type : Box
Molar Mass : 134-136 °C(lit.)
Medicine Type : Insoluble in water
Pack Size : 1 kg,5 kg, 10 kg,25kg
Composition : 1] Gao P, et al. Unexpected antitumorigenic effect of fenbendazole when combined with supplementary
Country of Origin : Made In India
...moreParacetamol Powder
400 - 600 Per Kilogram
25 Kilogram (MOQ)
Acetaminophen differs from the nonsteroidal anti-inflammatory agents described in that it is devoid of anti-inflammatory and antirheumatic properties. It was recently shown that acetaminophen, like aspirin, inhibits cyclooxygenase action in the brain and is even stronger than aspirin. On the other hand, the mechanism of analgesic action of acetaminophen is not fully clear, since it acts poorly on peripheral cyclooxygenase.Whether you call it acetaminophen (in the United States and Japan) or acetaminophen (in Europe and much of the rest of the world), it is one of the most widely used pain relievers. It was first proposed in 1878 by H.N. Morse. Although many studies were conducted on its use as an analgesic, it was not marketed under the name Triagesic until 1950. Today, its most common trade names are Tylenol and Panadol, but a large portion of its sales are generic versions.DescriptionAcetaminophen is an analgesic and antipyretic compound. Unlike many NSAIDs, which inhibit both COX-1 and COX-2, early studies suggested that acetaminophen is a poor inhibitor of both isoforms. However, it does inhibit COX-2 by 83% and COX-1 by 56% in human blood ex vivo, albeit at a high 1,000 mg dose, with IC50 values of 25.8 and 113.7 μM, respectively. Acetaminophen is enzymatically and non-enzymatically converted to several reactive metabolites that contribute to adverse or indirect effects, including liver injury. At toxic doses, the acetaminophen metabolite N-acetyl-4-benzoquinone imine (NAPQI; ) depletes glutathione reserves in the liver, leading to an accumulation of NAPQI and subsequent hepatocyte necrosis. Acetaminophen decreases glutathione levels and reduces glutathione peroxidase activity in mice when administered at a dose of 250 mg/kg and induces ferroptotic cell death in primary mouse hepatocytes, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 . Acetaminophen has analgesic and antipyretic properties in animal models.Acetaminophen is widely used as an analgesic and fever-reducing agent. Acetaminophen is designed for moderate analgesia. It is also effective like aspirin and is used in analgesia for headaches (from weak to moderate pain), myalgia, arthralgia, chronic pain, for oncological and post-operational pain, etcIn general, acetaminophen is used for the treatment of mild to moderate pain and reduction of fever. It is available over the counter in various forms, the most common being oral forms.Acetaminophen injection is indicated for the management of mild to moderate pain, the management of moderate to severe pain with adjunctive opioid analgesics, and the reduction of fever.Because of its low risk of causing allergic reactions, this drug can be administered in patients who are intolerant to salicylates and those with allergic tendencies, including bronchial asthmatics. Specific dosing guidelines should be followed when administering acetaminophen to children..
Brand Name : DOPRAN PHARMA
Color : White
Form : Powder
Application : NA
Grade : 99%
CAS No. : 103-90-2
EINECS No. : 203-157-5
Purity : 99%
Packaging Type : 25 KG
Type : Paracetamol Powder, NA
MF : CD00002328
Appearance : NA
Other Names : Acetaminophen
Active Ingredient : 1.5810 (rough estimate)
Country of Origin : India
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