Caspofungin Acetate For Injection 50 MG
101 - 500 Per Vial
1 Vial (MOQ)
Product Name: Caspofungin Acetate For InjectionBrand Name: CPCRStrength:50 MGPacking: Single Vial Per Box Pharmaceutical Composition: Caspofungin acetate, a lipopeptide antifungal agent, formulated as a powder for reconstitution into an intravenous solution. Mechanism of Action: Inhibits the synthesis of β-(1,3)-D-glucan, an essential component of fungal cell walls, leading to cell wall disruption and ultimately fungal cell death. Clinical Indications: Invasive Candidiasis: Used as a first-line treatment for invasive candidiasis, including candidemia and other forms of candidiasis, in patients who are unable to tolerate or have failed other antifungal therapies. Invasive Aspergillosis: Employed as salvage therapy for invasive aspergillosis, particularly in cases resistant to other antifungal agents. Empirical Antifungal Therapy: Considered in patients with febrile neutropenia who are at high risk of fungal infections, pending definitive diagnosis. Administration: Intravenous: Administered as a slow infusion over a designated period, typically once daily, with dosing adjusted based on patient's weight, renal function, and severity of infection. Precautions: Hepatic and Renal Function: Dosage adjustment may be necessary in patients with hepatic or renal impairment, as caspofungin is primarily metabolized in the liver and eliminated via the bile. Hypersensitivity: Caution is warranted in patients with known hypersensitivity reactions to echinocandins or any component of the formulation. Drug Interactions: Potential interactions with other medications, particularly those metabolized by cytochrome P450 enzymes, necessitating close monitoring and possible dosage adjustments. Monitoring: Regular monitoring of liver function tests, renal function, and clinical response recommended during therapy to assess efficacy and detect any adverse effects. Storage: Should be stored in accordance with pharmaceutical guidelines, typically at controlled room temperature, protected from light. Adverse Effects: Common adverse effects include gastrointestinal disturbances (nausea, vomiting, diarrhea), infusion-related reactions (fever, chills), and abnormalities in liver function tests. Caspofungin Acetate For Injection provides a valuable therapeutic option in the management of invasive fungal infections, offering broad-spectrum antifungal activity and convenient once-daily dosing when administered intravenously, with careful consideration of patient factors and potential adverse effects.
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