Tacrolimus Powder Dealers in Mumbai

• Type: WHITE CRYSTALLINE SOLID POWDER
• Color: WHITE CRYSTALLINE SOLID POWDER
• CAS No.: 104987-11-3
• WHITE CRYSTALLINE SOLID POWDER: WHITE CRYSTALLINE SOLID POWDER

Tacrolimus is a macrolide isolated from the culture broth of a strain of streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of t-lymphocytes in response to antigenic or mitogenic stimulation in vitro. Tacrolimus anhydrous is a calcineurin inhibitor immunosuppressant. The mechanism of action of tacrolimus anhydrous is as a calcineurin inhibitor. Anhydrous from of tacrolimus, a macrolide isolated from streptomyces tsukubaensis. Tacrolimus binds to the fkbp-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. This agent exhibits potent immunosuppressive activity in vivo & prevents the activation of t-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent.

• Synonyms: 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1;
• Cas Number: 104987-11-3
• Mol. Formula: C44H69NO12
• Mol.weight: 804.02
• Standard: Offered of Pharmaceutical Grade BP/USP/EP
• Packing: Offered in Export Worthy Packing of 25 Kilos or as per Our Customer Requirements
• Supplied By: UMA Brothers, India

Tacrolimus is a macrolide isolated from the culture broth of a strain of streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of t-lymphocytes in response to antigenic or mitogenic stimulation in vitro. Tacrolimus anhydrous is a calcineurin inhibitor immunosuppressant. The mechanism of action of tacrolimus anhydrous is as a calcineurin inhibitor.Anhydrous from of tacrolimus, a macrolide isolated from streptomyces tsukubaensis. Tacrolimus binds to the fkbp-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. This agent exhibits potent immunosuppressive activity in vivo & prevents the activation of t-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent.Tacrolimus Is A White Crystalline Solid Powder. It Is Soluble In Chloroform And Methanol With Melting Range Of 90°C TO 92°C.