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Coleus Forskohlii
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100 Kilogram (MOQ)
Coleus forskohlii is part of the mint family of plants and has long been cultivated in India, Thailand and parts of SE Asia as a spice and as a condiment for heart ailments and stomach cramps. The roots of the plant are a natural source of forskolin, the only plant-derived compound presently known to directly stimulate the enzyme adenylate cyclase, and subsequently cyclic AMP. PHYTOCHEMICALS : Chief alkaloid found is Forskohlii. Many other diterpenoids as deacetyl forskolin, 9-deoxyforskolin, 1, 9-deoxyforskolin,1, 9-dideoxy- 7-deacetylforskolin have been isolated. Other minor phytochemicals are allylroyleanone, barbatusin, plectrin, plectirinon A, acetoxycoleosol, coleol, coleonone, coleosol, deoxycoleonol, crocetin dialehyde, napthopyrones. PHARMACOKINETICS : Many of its effects come from a resultant increase in an enzyme called adenylate cyclase which increases the amount of cellular cyclic adenosine monophosphate (cAMP) which activates many other enzymes involved in diverse cellular functions. Increased cellular cAMP levels cause several physiological and biochemical effects such as Uses: Coleus is found to be effective in skin conditions as eczema and psoriasis. Coleus is primarily indicated for cardiovascular diseases including hypertension, congestive heart failure and angina Studies have indicated the use of coleus for asthma, intestinal colic, uterine cramps, as well as painful urination. Coleus can aid in weight loss due to its ability to breakdown stored fat as well as inhibit the synthesis of adipose tissue, additionally, it increases thyroid hormone production and release thereby increasing metabolism. Ophthalmic preparation of forskolin to the eyes lowers eye pressure thus reducing the risk of Glaucoma. Coleus can aid in digestive and malabsorption disorders through its ability to stimulate secretion of saliva, hydrochloric acid, pepsin, analyse, and pancreatic enzymes and increase nutrient absorption in the small intestine
