Antimalarial Drugs Dealers in Dandi Road, Surat

Proguanil (chloroguanide) is a biguanide; a synthetic derivative of pyrimidine. It was developed in 1945 by a british antimalarial research group. It has many mechanisms of action but primarily is mediated through conversion to the active metabolite cycloguanil. This inhibits the malarial dihydrofolate reductase enzyme. Its most prominent effect is on the primary tissue stages of p. Falciparum, p. Vivax and p. Ovale. It has no known effect against hypnozoites therefore is not used in the prevention of relapse. It has a weak blood schizonticidal activity and is not recommended for therapy of acute infection. However it is useful in prophylaxis when combined with atovaquone or chloroquine (in areas where there is no chloroquine resistance). 3 mgkg is the advised dosage per day, (hence approximate adult dosage is 200 mg). The pharmacokinetic profile of the drugs indicates that a half dose, twice daily maintains the plasma levels with a greater level of consistency, thus giving a greater level of protection. The proguanil- chloroquine combination does not provide effective protection against resistant strains of p. Falciparum.

Used to treat and prevent the life threatening disease, malaria, we are offering an effective range of Pharmaceutical Antimalarial Medicines. Our Pharmaceutical Antimalarial Medicines are most commonly used to treat malaria but they can also be prescribed for lupus and rheumatic arthritis. Our Pharmaceutical Antimalarial Medicines are manufactured in the hygienic environment using the quality ingredients and latest machinery. Besides, the Pharmaceutical Antimalarial Medicines can be taken from us at competitive price range.