S K Pharma Machinery Pvt Ltd Main Road, Thane, Maharashtra

SK's UNIPROSERVE offers precise control of shear energy introduction and therefore accurate control over particles and droplet size. The Homogenize is composed of an internal rotor-stator colloid tool. The oil and water phase mixes have exactly the same construction. There's a high speed disperser mounted from the top / bottom of the cover which helps to dissolve the ingredients.    FEATURES   Special Contra design of agitator blades Automatic lid opening system Efficient heating and cooling performance Accurate temperature control, even or small quantities Perfect particles and droplet size control Batch to batch repeatability High yield process Energy efficient (Heating / cooling / homogenizing / mixing) No mechanical seal in the vessel processing area High efficiency mixer Batch size – 50 kgs to 10000 kgs. Standard version           Pressure vessel with agitator Vacuum system Batch time improvement Homogenizer with Rotor Stator Double jacket with insulation Heating and cooling unit Lid lifting device User friendly control / visualization Option     Load cells and dosing units Comprehensive validation documentation   Recommended for   Tooth paste Shaving Cream Gel Denture Adhesives

S.K.'s biotechnology & Pharmaceutical specialist have years of experience solving problems related to liquid processes. Highly polished finishes on parts and attention to validation paperwork is given to satisfy all necessary industry requirements. From the largest national Biotechnology companies to the smallest pharmaceutical gel cap manufacturers for vitamins, customers have relied on S.K. for their essential plant and process requirement.    Key Features         Zero dead leg aseptic design of bottom outlet valve. Calibrated full view glass for the blending vessel. CIP & SIP style design vessel, fitting & piping. Volume monitoring by load cells. Process Automation. Steri connection flanges to avoid product contamination. Inbuilt CIP-SIP provided.   Agitator : Bottom driven agitator with double mechanical seal & thermosiphon, axial type, rpm variable speed. Functionally : Cleaning in place, Sterilization in place, fermentation process with temperature control, PH control, DO control. Jacket : Pressure gauge, safety valve, vent, chilled water supply & return, Drain, circular pump with heat exchangers for fine temperature control. Accessories       Spray ball, Pressure gauge, foam sensor, PH Sensor, Temperature sensor, vent line, Bottom outlet part, safety relief. Valve, Acid / Alkali / inoculam / feed addition lines with sterile four way valve, peristaltic pump, media filter (NFF type). Incinerator after exhaust filter. Working : Fully automatic.   Recommended for   Sterile Solution I V Fluied Vaccines Serums Large Volume Parantrals Small volume Parantrals Oncology Products    

CIP(Cleaning In Place) / SIP(Sterilization In Place) is an important part on the SK Pharma Machinery construction and development and is standard for all SK machines. A machine execution without dead area and the avoidance of the narrow gaps, screws, studs, seals and O-rings are the special characteristics of the SK Pharma Machinery machines. Minimize maintenance & optimized cleaning is the result. Many innovations are developed from this aspect only. CIP/SIP is a permanent element of the SK research and development.    Key Features The washing cycle are programmable and generate a validated cleaning in place cycle. The cycle steps are as below:  Hot RO water rinse and drain. Hot RO water recirculation and drain. Hot Alkali recirculation cycle and drain. Purified water recirculation and drain Acid recirculation cycle and drain. Purified water recirculation and drain. WFI wash and drain/

SEMIUNIPROSERVE – CREAM / GEL / OINTMENTS MANUFACTURING PLANT SK Homogenizer composed of an internal rotor-stator colloid tool, ensures excellent dispersal of droplet and particles efficiently.  With SK's SemiuniProserve, time for Homogenization are considerably shorter the smooth product design reduces wear on the parts, thus increasing their lifetime.    Key Features Complete Process of cleaning, dispersing, emulsifying, homogenizing, vacuum, heating 7 cooling in one unit. The homogenizer also works as a transfer pump for discharging finished products. Batch time improvement. Special semi contra design of agitator blades. Automatic lid opening system. Accurate temperature control even for small quantities. Perfect particles and droplet size control Batch to batch repeatability. Load cell for accurate weighing. Two line for product recirculation is provided to avoid wastage of materials (One is short and other is long). Standard version           Pressure vessel with agitator Vacuum system Batch time improvement Homogenizer with Rotor Stator Double jacket with insulation Heating and cooling unit Option       Various levels of automation Load cells and dosing units Comprehensive validation documentation   Recommended for   Cream Gel Lotion Emulsion Ointment Shampoo Conditioner Hand Washes Hair Cosmetics Products

The liquid manufacturing plant is a set of equipment designs for the manufacture of syrup, liquid oral formulations and other water based pharmaceutical products. The liquid manufacturing plants are ideal tool for the pharmaceutical industries for the production of oral liquid. It is specially designed to take care of two critical factors which directly affects the quality of the liquids. Minimum man-handling of liquid and effective hygiene during manufacturing. It also provides the benefits of the effective manpower utilization.    Key Features           50 ltr. – 30,000ltr. Batch mixers Complete untouchable process CIP / SIP able All wetted parts are of SS316/316 L Quality material. All pipelines are seamless & internally Electro polished. Sugar Changing Done under Vacuum. All transfer done under Vacuum. The Sugar syrup and manufacturing vessel are provided with limpet coils for heating and cooling and are designed with internal vacuum to facilitate transfer of sugar direct from stores to the sugar syrup vessel. The entry of all propeller agitator is from the bottom, through a specially designed mechanical seal face. The advantages of the bottom propeller agitator over conventional agitator are that, it includes no vibrations in the shaft and no coupling in the drive assembly, leading to lower maintenance cost. Inline filters to ensure filtration Inline Homogenizer is provided for making suspensions, with recirculation. Transfer Pump provided to transfer ready products to filling line. Load cell of accurate weighing FLP system can be provided (Optional)   The Facility Consist of       Side Vessel (Premix) Online side Vessel Prefilter Manufacturing Vessel and Storage vessel Vacuum system to transfer contents of side vessels to manufacturing vessels Product Piping Control Panel Transfer Pumps Batch size 50 Ltr. To 30,000 Ltr. Recommended for   Cough Syrup Drop Solutions Expectorant Suspensions

The liquid manufacturing plant is a set of equipment designs for the manufacture of syrup, liquid oral formulations and other water based pharmaceutical products. The liquid manufacturing plants are ideal tool for the pharmaceutical industries for the production of oral liquid. It is specially designed to take care of two critical factors which directly affects the quality of the liquids. The Sugar syrup and manufacturing vessel are provided with limpet coils for heating and cooling and are designed with internal vacuum to facilitate transfer of sugar direct from stores to the sugar syrup vessel.The advantages of the bottom propeller agitator over conventional agitator are that, it includes no vibrations in the shaft and no coupling in the drive assembly, leading to lower maintenance cost.

PILOT SCALE PLANT (R&D and Laboratory Purpose for Manufacturing) The special know-how of S.K. pharma machinery consists in rationalizing simple mixing processes and in solving most complicated mixing and processing task. This caters to laboratory scale as well as with bulk production. We have meanwhile solved numerous “impossible” mixing tasks together with our customer in our laboratory, where new mixing techniques and procedures are continuously developed and tested in practice. The Homogenizers, the Turbo-Dissolvers, anchor/ scaper agitator, co-axial agitator, magnetic agitator etc. of S.K. Pharma Machinery are in use worldwide.    Innovations of S.K. Pharma   Technical Features   SK-Homogenizer with shearing-intensive “homogenizing” mode or “pumping” mode with low shearing effect, simply achieved by the change in direction of rotation and special geometry. S.K. Pharma Machinery agitator and scraper systems with vertical and horizontal mixing effect for shortest heating and cooling time. Integrated CIP/SIP, suitable for pharmaceuticals production. Batch size minimum 1 kg to maximum 10kg. Technical Features   Heating / Cooling and insulated jackets complete with temperature control and safety equipments. Anchor agitator with open slot scraper design. Short loop product RE-Circulation for smaller batch sizes. Tilting of manufacturing vessel top dish to facilitate product recovery. Separate pre-mix vessel for oil and aqueous phase. Process piping with transfer panel design for automated plants. Cleaning in place cycles with validation protocols.

SK Homogenizer composed of an internal rotor-stator colloid tool, ensures excellent dispersal of droplet and particles efficiently. Complete Process of cleaning, dispersing, emulsifying, homogenizing, vacuum, heating 7 cooling in one unit.Two line for product recirculation is provided to avoid wastage of materials (One is short and other is long).