Saikrishnaa Associates Polepettai, Thoothukudi, Tamil Nadu

Trabectedin (also known as ecteinascidin 743 or et-743) is an anti-tumor drug. It is sold by zeltia and johnson and johnson under the brand name yondelis. It is approved for use in europe, russia and south korea for the treatment of advanced soft tissue sarcoma. It is also undergoing clinical trials for the treatment of breast, prostate, and paediatric sarcomas. The european commission and the u.s. Food and drug administration (fda) have granted orphan drug status to trabectedin for soft tissue sarcomas and ovarian cancer.

Vinorelbine Injection The primary use of the drug is to treat breast cancer. In addition, it is also used for the purpose of fighting non small cell lung cancer. Its effectiveness is because of the perfect composition this product is made up of. Vinorelbine is cancer medication that interferes with the growth of cancer cells and slows their spread in the body. Vinorelbine is used to treat non-small cell lung cancer. Vinorelbine is sometimes used in combination with other cancer medications Generic name is Navelbine. Features: Treats breast cancer Treats non small cell lung cancer Highly effective Perfect composition

Verteporfin (trade name visudyne), a benzoporphyrin derivative, is a medication used as a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light with a wavelength of 693 nm in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to the endothelium and blockage of the vessels.

Beractant, also known by the trade name of survanta®, is a modified bovine surfactant extract. As an intratracheal suspension, it can be used for the prevention and treatment for neonatal respiratory distress syndrome.

Rituximab (trade names rituxan and mabthera, ristova) is a chimeric monoclonal antibody against the protein cd20, which is primarily found on the surface of immune system b cells (this should not be confused with pancreatic β- or beta cells).

Rho(D) Immune Globulin is a medicine given by intramuscular injection that is used to prevent the immunological condition known as Rhesus disease (or hemolytic disease of newborn). The medicine is a solution of IgG anti-D (anti-RhD) antibodies that suppresses the mother’s immune system from attacking Rh-positive blood cells which have entered the maternal blood stream from fetal circulation.

Etanercept (trade name Enbrel) is a biopharmaceutical that treats autoimmune diseases by interfering with tumor necrosis factor (TNF; a soluble inflammatory cytokine) by acting as a TNF inhibitor. It has U.S. F.D.A. approval to treat rheumatoid, juvenile rheumatoid and psoriatic arthritis, plaque psoriasis and ankylosing spondylitis. TNF-alphais the “master regulator” of the inflammatory (immune) response in many organ systems. Autoimmune diseases are caused by an overactive immune response. Etanercept has the potential to treat these diseases by inhibiting TNF-alpha.

Benzatropine (inn), also known as benztropine (usan, ban), is an anticholinergic marketed under the trade name cogentin which is used in the treatment of parkinson’s disease, parkinsonism, and dystonia.

Avonex (interferon beta-1a) is made from human proteins. Avonex is a medication manufactured by a biotechnological process from one of the naturally-occurring interferons. It is made up of exactly the same amino acids as the interferon beta found in the human body. Avonex is in a class of drugs known as immunomodulators, which work by acting on the immune system. Avonex is used to treat relapsing multiple sclerosis. Avonex may also be used for purposes not listed in this medication guide. Manufacturer: biogen idec. Packing: 1 vial.

Atgam – atgam is a lymphocyte-selective immunosuppressant, prescribed for prevention of organ rejection during transplantation. It is also used in aplastic anemia. Indications: atgam is a lymphocyte-selective immunosuppressant, prescribed for prevention of organ rejection during transplantation. It is also used in aplastic anemia. contraindications: hypersensitivity. Dosage: for organ rejection- adult- the recommended dose is 10 to 30 mgkg of body weight daily. Child- the recommended dose is 5 to 25 mgkg daily.

Amphotericin b (fungilin, fungizone, abelcet, ambisome, fungisome, amphocil, amphotec) is a polyene antifungal drug, often used intravenously for systemic fungal infections. Its name originates from the chemical’s amphoteric properties. Two amphotericins, amphotericin a and amphotericin b are known, but only b is used clinically, because it is significantly more active in vivo. Amphotericin a is almost identical to amphotericin b (having a double c=c bond between the 27th and 28th carbons), but has little antifungal activity. Currently, the drug is available as plain amphotericin b, as a cholesteryl sulfate complex (abcd), as a lipid complex (ablc), and as a liposomal formulation (lamb). The latter formulations have been developed to improve tolerability for the patient, but may show considerably different pharmacokinetic characteristics compared to plain amphotericin b.

Bacillus calmette–guérin (historically vaccin bilié de calmette et guérin commonly referred as bacille de calmette et guérin or bcg) is a vaccine against tuberculosis that is prepared from a strain of the attenuated (weakened) live bovine tuberculosis bacillus, mycobacterium bovis, that has lost its virulence in humans by being specially subcultured in a culture medium, usually middlebrook 7h9 middlebrook_7h9_broth.

Leuprolide acts as an agonist at pituitary GnRH receptors. By interrupting the normal pulsatile stimulation of, and thus desensitizing, the GnRH receptors, it indirectly downregulates the secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to hypogonadism and thus a dramatic reduction in estradiol and testosterone levels in both sexes.

Trastuzumab (inn; trade names herclon, herceptin) is a monoclonal antibody that interferes with the her2neu receptor. Its main use is to treat certain breast cancers.